Can you get AIDS from oral sex?  First off, HIV (human immunodeficiency virus) is the infection that causes AIDS (acquired immune deficiency syndrome), which is the most advanced stage of HIV disease. So AIDS can’t be spread through sex play, but HIV can.Second, it IS possible to get HIV from unprotected oral sex, but the risk is considered low.HIV is spread through blood, semen, pre-ejaculate, vaginal fluids, and breast milk. So, in the case of unprotected oral sex, an HIV-positive person could pass the virus on if their blood, semen, pre-ejaculate, or vaginal secretions got into any open wounds or sores in another person’s mouth or gums.Using condoms (on a male) or Glyde dams (on a female) for oral sex can help reduce the risk.