Is the abortion pill safe? Yes, the abortion pill (also called mifepristone, RU-486, or medication abortion) is considered a safe, effective, and legal method to terminate a pregnancy.Most women can have a medication abortion safely and confidentially. But all medical procedures have some risks, and it’s up to you to decide whether the benefits outweigh the risks.The abortion pill can only be given by a doctor or health care professional. They’ll determine whether you qualify for a medication abortion (it is only available to women in the early weeks of pregnancy) and discuss the risks with you at your appointment.